Ativan is a preparation that is characterized by anxiolytic and hypnotic and sedative effects. The lorazepam contained in it primarily affects the limbic system and hypothalamus.
The drug is recommended to be given in the case of anxiety disorders of various etiologies, which occur with diseases of the circulatory system, gastrointestinal tract; as well as sleep disorders associated with states of increased anxiety. Use temporarily and for a short time.
The product contains lorazepam, which belongs to the category of 1,4-benzodiazepine derivatives. It affects a significant number of structures within the central nervous system, especially on the limbic system and hypothalamus, i.e. structures related to the normalization of the emotional activities of the body. It intensifies the blocking action of GABAergic nerve cells in the cerebral cortex, hippocampus, cerebellum, thalamus and hypothalamus. The preparation increases the affinity of the GABAergic receptor to gamma-aminobutyric acid (GABA), which is an endogenous neurotransmitter with inhibitory properties. The active substance of the drug has an anxiolytic and hypnotic effect.
- – allergy to the constituent substances of the drug
- – severe respiratory failure (regardless of its aetiology)
- – severe kidney and liver problems
- – Erb-Goldflam disease
- – glaucoma
- – acute porphyria
- – alcohol poisoning
- – night sleep apnea syndrome
Use orally. The dose and duration of the treatment should be determined individually for each patient. In the case of adults and adolescents over 12 years of age with anxiety disorders, 2-3 mg / 24h is usually administered initially (in 2-3 divided doses). If necessary, the dose may be increased to a maintenance dose of 2-6 mg / 24h (in 2-3 divided doses). Do not use more than 10 mg / 24h. For sleep disorders, usually give 2-4 mg x 1 / 24h before going to bed.